We have been fulltimers since 1998, most of that time in a fifth wheel.
You don't say where you live or what kind of tow vehicle you have. If you live someplace where it gets extremely cold in the winter...or extremely hot in the summer...it will take a bit more work to make an RV (of any type) comfortable in those extreme conditions, but it can be done. And concerning your tow vehicle, just make sure you have enough truck to safely pull the weight of your fifth wheel (think GVWR of the fifth wheel, not dry weight).
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